Ibuprofenum, Codeini phosphas hemihydricus

Medicinal product name Brufen Plus 400 mg/30 mg film-coated tablets
Pharmaceutical form Film-coated tablet
Strength 400 mg/30 mg 
Information from the MAH on shortages Not available
predicted availability date: not notified
Legal status Rx Prescription (Pr.)
Package leafletPDF 28-03-2023
Summary of product characteristicsPDF 28-03-2023
Risk minimisation measuresVēstule veselības aprūpes speciālistam Vēstule veselības aprūpes speciālistam
ATC code N02AJ08 Analgesics
Information for Marketing authorisation holdersView

Important notice

Additional information regarding the use for persons aged 75+

If used as "ANALGESICS"
IbuprofenumCSuitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. Note increased risk of gastrointestinal bleeding and cardiovascular events. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
Codeini phosphas hemihydricusDAvoid use in older persons. Opioid. Sedative. Prodrug. Genotype affects the response. Significant adverse effects include constipation, nausea, urinary difficulties and gallbladder problems. Increases risk of falling. Take interactions into account.

Medicinal products (1)

Availability of medicinal product Wholesalers Package size, content Primary packaging Maximum admissible pharmacy price (€ incl. VAT) Product No. Labelling
 Not available (according to the information provided by wholesalers)
predicted availability date: not notified
currently no information on availability from any wholesaler N30
(400 mg/30 mg)
Al/PVDC//PVC/PVDC blister    14-0009-01 Labelling text Labelling text Aug 18, 2022

Registration information

Marketing authorisation No. 14-0009
Date of authorisation Jan 20, 2014
Marketing authorisation holder, country Viatris Healthcare Limited, Ireland